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Article

Hypertension, antihypertensives and mutations in the Von Hippel-Lindau gene in renal cell carcinoma: results from the Netherlands Cohort Study.

Journal of hypertension - 1 Nov 2005

Schouten Leo J, van Dijk Boukje A C, Oosterwijk Egbert, Hulsbergen-van de Kaa Christina A, Kiemeney Lambertus A L M, Goldbohm R Alexandra, Schalken Jack A, van den Brandt Piet A

Abstract excerpt

OBJECTIVES: Hypertension and/or antihypertensive medication are reported to be risk factors of renal cell carcinoma (RCC). We investigated whether these risk factors are associated with von Hippel-Lindau gene (VHL) mutations in RCC. METHODS: The Netherlands Cohort Study on Diet and Cancer (NLCS) started in 1986 (n = 120 852 men and women) and uses the case-cohort methodology. After 11.3 years of follow-up, 337...

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Identifiers

PMID: 16208141
DOI: 10.1097/01.hjh.0000186023.74245.48

Genes

VHL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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