Article
Alcohol consumption and mutations or promoter hypermethylation of the von Hippel-Lindau gene in renal cell carcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2008
Schouten Leo J, van Dijk Boukje A C, Oosterwijk Egbert, van Engeland Manon, Hulsbergen-van de Kaa Christina A, Kiemeney Lambertus A L M, Goldbohm Royle Alexandra, Kester Arnold, de Vogel Stefan, Schalken Jack A, van den Brandt Piet A
Abstract excerpt
Alcohol consumption has been associated with a decreased risk for renal cell cancer in several studies. We investigated whether alcohol is associated with (epi)genetic changes of the von Hippel-Lindau (VHL) gene in renal cell cancer. The Netherlands Cohort Study (NLCS) on Diet and Cancer started...
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