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Article

Activating mutations of Gsalpha in kidney cancer.

The Journal of urology - 1 Sept 2006

Kalfa Nicolas, Lumbroso Serge, Boulle Nathalie, Guiter Jacques, Soustelle Laurent, Costa Pierre, Chapuis Heliette, Baldet Pierre, Sultan Charles

Abstract excerpt

PURPOSE: Heterotrimeric G proteins are signal transduction proteins coupled to hormone receptors that activate intracellular second messenger systems, mainly cyclic adenosine monophosphate mediated protein kinase. Recent studies indicate that G proteins may have a major role in oncogenesis as well as in tumor invasiveness and cell proliferation. The involvement of G proteins was formerly thought to be limited to...

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Source

Identifiers

PMID: 16890646
DOI: 10.1016/j.juro.2006.04.023

Genes

GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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