Article
G protein gene mutations in patients with multiple endocrinopathies.
The Journal of clinical endocrinology and metabolism - 1 May 1995
Williamson E A, Johnson S J, Foster S, Kendall-Taylor P, Harris P E
Abstract excerpt
Point mutations of G protein genes that result in the constitutive activation of G proteins have been described. Such mutations have been shown to occur in a number of endocrine diseases. We have examined tissues from patients having more than one organ affected by an endocrine disorder and patie...
Topics
- Adult
- Base Sequence
- DNA, Neoplasm
- Female
- GTP-Binding Proteins
- Humans
- Male
- Middle Aged
- Molecular Probes
- Molecular Sequence Data
- Multiple Endocrine Neoplasia
- Mutation