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Article

The estrogen receptor alpha C975G variant in familial and sporadic breast cancer: a case-control study.

Anticancer research - 1 Jan 2000

Skoglund Johanna, Margolin Sara, Zhou Xiao-Lei, Maguire Paula, Werelius Barbro, Lindblom Annika

Abstract excerpt

BACKGROUND: The estrogen receptor alpha (ESR1) mediates the effect of estrogen in target tissues. Estrogen is important in breast cancer development and several polymorphic variants in the ESR1 gene have been investigated for association with breast cancer. The C975G variant is the most extensively studied and has been suggested to be a risk factor. MATERIALS AND METHODS: The frequency of the C975G variant was...

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Source

Identifiers

PMID: 16886637

Genes

BRCA1
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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