Article
A common polymorphism near the ESR1 gene is associated with risk of breast cancer: evidence from a case-control study and a meta-analysis.
PloS one - 1 Jan 2012
Guo Hui, Ming Jie, Liu Chunping, Li Zhi, Zhang Ning, Cheng Hongtao, Wang Wei, Shi Wei, Shen Na, Zhao Qunzi, Li Dapeng, Yi Pengfei, Wang Longqiang, Wang Rui, Xin Yue, Zhao Xiangwang, Nie Xiu, Huang Tao
Abstract excerpt
BACKGROUND: Genome-wide association studies have reported that a polymorphism near the estrogen receptor gene (ESR1) (rs2046210) is associated with a risk of breast cancer, with the A allele conferring an increased risk. However, considering the controversial results from more recent replicated studies, we conducted a case-control study in an independent Chinese Han population and a meta-analysis to clarify the...
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