Article
A Meta-Analysis of the Association between ESR1 Genetic Variants and the Risk of Breast Cancer.
PloS one - 1 Jan 2016
Li Taishun, Zhao Jun, Yang Jiaying, Ma Xu, Dai Qiaoyun, Huang Hao, Wang Lina, Liu Pei
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in the estrogen receptor gene (ESR1) play critical roles in breast cancer (BC) susceptibility. Genome-wide association studies have reported that SNPs in ESR1 are associated with BC susceptibility; however, the results of recent studies have been inconsistent. Therefore, we performed this meta-analysis to obtain more accurate and credible results. METHODS: We...
Topics
- Alleles
- Asian People
- Breast Neoplasms
- Case-Control Studies
- Cohort Studies
- Estrogen Receptor alpha
- Female
- Genetic Predisposition to Disease
- Genetic Variation
- Genome-Wide Association Study
- Genotype