Article
HLA DQA1 and DQB1 study in Algerian type 1 diabetes families.
Diabete & metabolisme - 1 Jan 2000
Beressi J P, Djoulah S, Khalil I, Benhamamouch S, Bessaoud K, Touhami M, Hors J, Deschamps I
Abstract excerpt
The distribution of HLA class II alleles associated with insulin-dependent diabetes mellitus (Type 1) in the Algerian population is poorly known. We have typed 36 Algerian Type 1 diabetic probands and their families using DQA1 and DQB1 oligonucleotide probes. Fifty-nine parental haplotypes non transmitted to diabetic offspring served as controls. The frequencies of DQA1 and DQB1 alleles and haplotypes and their...
Topics
- Algeria
- Consanguinity
- Diabetes Mellitus, Type 1
- Female
- France
- Genotype
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- Haplotypes
- Heterozygote
- Homozygote
