Article
HLA class II allele frequencies in type 1A diabetes mellitus Slovak patients.
Bratislavske lekarske listy - 1 Jan 2006
Shawkatova I, Michalkova D, Barak L, Fazekasova H, Kuba D, Buc M
Abstract excerpt
BACKGROUND: Diabetes mellitus type 1A (DM-1A) is an autoimmune disease in which the immune response is directed to pancreatic islet cells. DM-1A occurs in genetically predisposed individuals. Among type 1A diabetes associated genes, those of the HLA region have the greatest effect. OBJECTIVES: The aim of our study was to obtain a comprehensive survey of the HLA-DRB1 and HLA-DQB1 allele frequencies in Slovak...
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