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Article

HLA class II gene associations in African American type 1 diabetes reveal a protective HLA-DRB1*03 haplotype.

Diabetic medicine : a journal of the British Diabetic Association - 1 Jun 2013

Howson J M M, Roy M S, Zeitels L, Stevens H, Todd J A

Abstract excerpt

AIMS: Owing to strong linkage disequilibrium between markers, pinpointing disease associations within genetic regions is difficult in European ancestral populations, most notably the very strong association of the HLA-DRB1*03-DQA1*05:01-DQB1*02:01 haplotype with Type 1 diabetes risk, which is assumed to be because of a combination of HLA-DRB1 and HLA-DQB1. In contrast, populations of African ancestry have greater...

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Identifiers

PMID: 23398374
DOI: 10.1111/dme.12148
PMCID: PMC3709123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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