Article
Metagenomic DNA fragments that affect Escherichia coli mutational pathways.
Molecular microbiology - 1 Aug 2006
Yang Hanjing, To Kam H, Aguila Sharon J, Miller Jeffrey H
Abstract excerpt
A multicopy cloning approach was used to search for metagenomic DNA fragments that affect Escherichia coli mutational pathways. Soil metagenomic expression libraries were constructed with DNA samples prepared directly from soil samples collected from the UCLA Botanical Garden. Using frameshift mutator screening, we obtained a total of 26 unique metagenomic fragments that stimulate frameshift rates in an E. coli...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
