Article
Association between CD14 gene polymorphisms and disease phenotype in sarcoidosis.
Respiratory medicine - 1 Sept 2010
Fridlender Zvi G, Schwartz Asaf, Kohan Martin, Amir Gail, Glazer Mendel, Berkman Neville
Abstract excerpt
Although the etiology of sarcoidosis is unknown, genetic susceptibility has been demonstrated. Granuloma formation is a key feature in the pathophysiology of sarcoidosis and Crohn's Disease, raising the possibility that these diseases share common pathogenetic pathways. An association between sarcoidosis and the protein "CD14", a molecule that is part of the lipopolysaccharide (LPS) cell surface receptor complex,...
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