Article
Polymorphisms and haplotypes in MyD88 are associated with the development of sarcoidosis: a candidate-gene association study.
Molecular biology reports - 1 Jul 2013
Daniil Z, Mollaki V, Malli F, Koutsokera A, Antoniou K M, Rodopoulou P, Gourgoulianis K, Zintzaras E, Vassilopoulos G
Abstract excerpt
Sarcoidosis is considered as a disorder of protracted immune response to an as yet unidentified causative agent that leads to granuloma formation. Material from M. tuberculosis and P. acne has been repeatedly detected in the sarcoidosis lesions, implying the involvement of the Toll-like receptor2 (TLR2) gene that responds to these intracellular pathogens. Since TLR2 association studies have produced controversial...
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