Article
Apoptotic cleavage of rabaptin-5-like proteins and a model for rabaptin-5 inactivation in apoptosis.
Cell cycle (Georgetown, Tex.) - 1 Aug 2006
Korobko Elena V, Palgova Irina V, Kiselev Sergey L, Korobko Igor V
Abstract excerpt
Intracellular membrane transport from the plasma membrane is one of the processes affected in apoptotic cells. Apoptotic inhibition of endosomal transport occurs due to cleavage of Rabaptin-5, an effector of small GTPase Rab5, which results in inhibition of early endosome fusion. Recently several novel Rabaptin-5-like proteins were identified. We investigated whether Rabaptin-5-like proteins, Rabaptin-5gamma and...
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