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Article

HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8.

Molecular and cellular biology - 1 Jan 2004

Chen Hexin, Chung Seung, Sukumar Saraswati

Abstract excerpt

HOXA5 is a transcriptional factor whose expression is lost in more than 60% of breast carcinomas. Our previous work demonstrated that the overexpression of HOXA5 in MCF7 cells resulted in cell death through a p53-dependent apoptotic pathway. To determine whether p53-independent apoptotic pathways...

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Identifiers

PMID: 14701762
DOI: 10.1128/MCB.24.2.924-935.2004
PMCID: PMC343791

Genes

HOXA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14701762-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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