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Article

The needle component of the type III secreton of Shigella regulates the activity of the secretion apparatus.

The Journal of biological chemistry - 30 Dec 2005

Kenjale Roma, Wilson Justin, Zenk Sebastian F, Saurya Saroj, Picking Wendy L, Picking William D, Blocker Ariel

Abstract excerpt

Gram-negative bacteria commonly interact with eukaryotic host cells by using type III secretion systems (TTSSs or secretons). TTSSs serve to transfer bacterial proteins into host cells. Two translocators, IpaB and IpaC, are first inserted with the aid of IpaD by Shigella into the host cell membrane. Then at least two supplementary effectors of cell invasion, IpaA and IpgD, are transferred into the host cytoplasm....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16227202
DOI: 10.1074/jbc.M508377200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The needle component of the type III secreton of Shigella regulates the activity of the secretion apparatus.PMID 16227202Read ↗

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