Article
Complex interaction of Drosophila GRIP PDZ domains and Echinoid during muscle morphogenesis.
The EMBO journal - 9 Aug 2006
Swan Laura E, Schmidt Manuela, Schwarz Tobias, Ponimaskin Evgeni, Prange Ulrike, Boeckers Tobias, Thomas Ulrich, Sigrist Stephan J
Abstract excerpt
Glutamate receptor interacting protein (GRIP) homologues, initially characterized in synaptic glutamate receptor trafficking, consist of seven PDZ domains (PDZDs), whose conserved arrangement is of unknown significance. The Drosophila GRIP homologue (DGrip) is needed for proper guidance of embryonic somatic muscles towards epidermal attachment sites, with both excessive and reduced DGrip activity producing...
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