The Drosophila abrupt gene encodes a BTB-zinc finger regulatory protein that controls the specificity of neuromuscular connections.

doi:10.1101/gad.9.23.2936

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Article

The Drosophila abrupt gene encodes a BTB-zinc finger regulatory protein that controls the specificity of neuromuscular connections.

Genes & development - 1 Dec 1995

Hu S, Fambrough D, Atashi J R, Goodman C S, Crews S T

Abstract excerpt

Motor axons make synaptic connections with specific muscles, and this specificity unfolds during development as motoneuron growth cones make specific pathway choices and ultimately recognize and synapse on their specific muscle targets. The Drosophila clueless mutation was identified previously in a genetic screen for mutations that disrupt motoneuron guidance and connectivity. We show here that clueless is...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Cell Nucleus
Cloning, Molecular
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
Genes, Insect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Motor Neurons

Muscle Development

Muscles

Mutation

Nervous System

Sequence Alignment

Source

Open in PubMed

Identifiers

PMID: 7498790
DOI: 10.1101/gad.9.23.2936

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7498790-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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