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Article

Sequence-based analysis of the CYP2D636-CYP2D610 tandem-type arrangement, a major CYP2D6*10 haplotype in the Japanese population.

Drug metabolism and pharmacokinetics - 1 Jun 2006

Soyama Akiko, Saito Yoshiro, Kubo Takashi, Miyajima Atsuko, Ohno Yasuo, Komamura Kazuo, Ueno Kazuyuki, Kamakura Shiro, Kitakaze Masafumi, Tomoike Hitonobu, Ozawa Shogo, Sawada Jun-ichi

Abstract excerpt

The frequency of the CYP2D6*10 allele (100C>T) in the Japanese is relatively high (0.3-0.4), and the two *10-related genes, Ch1 (currently *10B) and Ch2 (*36), and their tandem arrangement Ch(2)-Ch(1) (*36-*10B) have been reported. Although the tandem form of *36-*10 is assumed to be a major form, no detailed information has been reported for its intervening and flanking regions. Thus in this study, the...

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PMID: 16858124
DOI: 10.2133/dmpk.21.208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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