Article
Three novel single nucleotide polymorphisms (SNPs) of the CYP2B6 gene in Japanese individuals.
Drug metabolism and pharmacokinetics - 1 Apr 2004
Hiratsuka Masahiro, Hinai Yudai, Konno Yumiko, Nozawa Hisayoshi, Konno Shoetsu, Mizugaki Michinao
Abstract excerpt
We sequenced all exons and exon-intron junctions of the CYP2B6 gene from 200 Japanese individuals. We found three novel single nucleotide polymorphisms (SNPs) (1375A>G, 1427G>A and 1454A>T) causing amino acid substitutions (Met(459)Val, Gly(476)Asp and Gln(485)Leu in exon 9), respectively. The de...
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