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Article

CYP2D6 allele frequencies, copy number variants, and tandems in the population of Hong Kong.

Journal of clinical laboratory analysis - 1 Jan 2019

Chan Wing, Li Man S, Sundaram Senthil K, Tomlinson Brian, Cheung Pik Y, Tzang Chi H

Abstract excerpt

BACKGROUND: CYP2D6 plays a crucial role in drug metabolism of several drugs. It is known to be highly polymorphic with enzymatic activity ranging from poor to ultrarapid metabolic rates. While the frequencies of CYP2D6 alleles are generally known in different Asian populations, data on frequencies of the copy number variations (CNV) and tandems in CYP2D6 in which they occur are less well studied in these...

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Identifiers

PMID: 30069923
DOI: 10.1002/jcla.22634
PMCID: PMC6430334

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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