Article
Novel nonsynonymous single nucleotide polymorphisms in the CYP2D6 gene.
Drug metabolism and pharmacokinetics - 1 Aug 2004
Soyama Akiko, Kubo Takashi, Miyajima Atsuko, Saito Yoshiro, Shiseki Kisho, Komamura Kazuo, Ueno Kazuyuki, Kamakura Shiro, Kitakaze Masafumi, Tomoike Hitonobu, Ozawa Shogo, Sawada Jun-ichi
Abstract excerpt
Cytochrome P450 (CYP) 2D6 is an important drug-metabolizing enzyme, and its gene is known to be highly polymorphic. Here, we report five novel nonsynonymous single nucleotide polymorphisms (SNPs), and 65 other sequence variations detected from the gene coding for cytochrome P450 (CYP) 2D6 in 254...
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