Article
Molecular aspects of chemical carcinogenesis: the roles of oncogenes and tumour suppressor genes.
Toxicology - 27 Feb 1995
Stanley L A
Abstract excerpt
The observation that oncogenes are frequently activated in human tumours raises the question of whether these genes are involved in chemical carcinogenesis. H-ras activation is probably an initiating event in mouse skin and rat mammary gland systems. The H-ras oncogene is also important in mouse...
Topics
- Animals
- Base Sequence
- Carcinogens
- Codon
- Disease Models, Animal
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Genes, ras
- Humans
- Liver Neoplasms, Experimental
- Lung Neoplasms
- Mammary Neoplasms, Experimental
