Mechanism of carcinogenesis: the role of oncogenes, transcriptional enhancers and growth factors.

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Article

Mechanism of carcinogenesis: the role of oncogenes, transcriptional enhancers and growth factors.

Anticancer research - 1 Jan 2000

Spandidos D A

Abstract excerpt

The oncogenes are a set of genes that have been implicated as the basis of cancer. They are the activated forms of proto-oncogenes which are part of the genetic complement of all normal cells. Activation can result from mutations in the global sense i.e. point mutations, nucleotide deletions or i...

Topics

Animals
Cell Line
Cell Transformation, Neoplastic
Cricetinae
DNA, Recombinant
Enhancer Elements, Genetic
Gene Expression Regulation
Genes, Regulator
Growth Substances
Humans
Mice
Neoplasm Proteins
Neoplasms
Oncogenes
Phenotype
Proto-Oncogene Proteins p21(ras)
Rats
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 3904595

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-3904595-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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