Article
Mechanism of carcinogenesis: the role of oncogenes, transcriptional enhancers and growth factors.
Anticancer research - 1 Jan 2000
Spandidos D A
Abstract excerpt
The oncogenes are a set of genes that have been implicated as the basis of cancer. They are the activated forms of proto-oncogenes which are part of the genetic complement of all normal cells. Activation can result from mutations in the global sense i.e. point mutations, nucleotide deletions or insertions, and chromosomal translocations. These mutations induce quantitative or qualitative changes in oncogene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.