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Article

Neofunctionalization in vertebrates: the example of retinoic acid receptors.

PLoS genetics - 1 Jul 2006

Escriva Hector, Bertrand Stéphanie, Germain Pierre, Robinson-Rechavi Marc, Umbhauer Muriel, Cartry Jérôme, Duffraisse Marilyne, Holland Linda, Gronemeyer Hinrich, Laudet Vincent

Abstract excerpt

Understanding the role of gene duplications in establishing vertebrate innovations is one of the main challenges of Evo-Devo (evolution of development) studies. Data on evolutionary changes in gene expression (i.e., evolution of transcription factor-cis-regulatory elements relationships) tell only part of the story; protein function, best studied by biochemical and functional assays, can also change. In this...

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Share to Gene Expression Regulation, Developmental
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16839186
DOI: 10.1371/journal.pgen.0020102
PMCID: PMC1500811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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