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Article

Neofunctionalization of Androgen Receptor by Gain-of-Function Mutations in Teleost Fish Lineage.

Molecular biology and evolution - 1 Jan 2016

Ogino Yukiko, Kuraku Shigehiro, Ishibashi Hiroshi, Miyakawa Hitoshi, Sumiya Eri, Miyagawa Shinichi, Matsubara Hajime, Yamada Gen, Baker Michael E, Iguchi Taisen

Abstract excerpt

Steroid hormone receptor family provides an example of evolution of diverse transcription factors through whole-genome duplication (WGD). However, little is known about how their functions have been evolved after the duplication. Teleosts present a good model to investigate an accurate evolutionary history of protein function after WGD, because a teleost-specific WGD (TSGD) resulted in a variety of duplicated...

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PMID: 26507457
DOI: 10.1093/molbev/msv218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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