Article
[Genetic control of the development by retinoic acid].
Comptes rendus des seances de la Societe de biologie et de ses filiales - 1 Jan 1997
Mark M, Kastner P, Ghyselinck N B, Krezel W, Dupé V, Chambon P
Abstract excerpt
Two families of nuclear receptors for retinoic acid (RA) have been characterized. Members of the RAR family (types alpha, beta and gamma and their isoforms alpha 1, alpha 2, beta 1 to beta 4, and gamma 1 and gamma 2) are activated by most physiologically occurring retinoids (all-trans RA, 9-cis RA, 4oxo RA and 3,4 dihyroRA). In contrast, members of the RXR family (types alpha, beta and gamma and their isoforms)...
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