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Chronicle of a discovery: the retinoic acid receptor

21 Jul 2022

Abstract excerpt

The landmark 1987 discovery of the retinoic acid receptor (RAR) came as a surprise, uncovering a genomic kinship between the fields of vitamin A biology and steroid receptors. This stunning breakthrough triggered a cascade of studies to deconstruct the roles played by the RAR and its natural and synthetic ligands in embryonic development, skin, growth, physiology, vision, and disease as well as providing a...

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PMID: 35900848
DOI: 10.1530/jme-22-0117

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