Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of the JAK2(V617F) mutation in myeloproliferative disorders by melting curve analysis using the LightCycler system.

Archives of pathology & laboratory medicine - 1 Jul 2006

Olsen Randall J, Tang Zhouwen, Farkas Daniel H, Bernard David W, Zu Youli, Chang Chung-Che

Abstract excerpt

CONTEXT: A specific mutation, JAK2(V617F), was recently recognized as having diagnostic value for myeloproliferative disorders. No practical assay is currently available for routine use in a clinical laboratory. OBJECTIVE: We report the development of a real-time polymerase chain reaction melting curve analysis assay that is appropriate for molecular diagnostics testing. DESIGN: Specific primers and fluorescence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Fluorescence Resonance Energy Transfer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Janus Kinase 2

Share to Leukemia, Myeloid

Share to Molecular Diagnostic Techniques

Share to Myeloproliferative Disorders

Share to Protein-Tyrosine Kinases

Share to Transition Temperature

Source

Identifiers

PMID: 16831057
DOI: 10.5858/2006-130-997-DOTJMI

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of the JAK2(V617F) mutation in myeloproliferative disorders by melting curve analysis using the LightCycler system.PMID 16831057Read ↗

Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis.Semantic proximity Read ↗

Rapid identification of heterozygous or homozygous JAK2(V617F) mutations in myeloproliferative neoplasms using melting curve analysis.Semantic proximity Read ↗

Identification of theJAK2V617F Mutation in Chronic Myeloproliferative Disorders Using FRET Probes and Melting Curve AnalysisSemantic proximity Read ↗

Clinical Performance of <i>JAK2</i> V617F Mutation Detection Assays in a Molecular Diagnostics LaboratorySemantic proximity Read ↗

Validating the Sensitivity of High-Resolution Melting Analysis for JAK2 V617F Mutation in the Clinical Setting.Semantic proximity Read ↗

Melting point assay for the JAK2 V617F mutation, comparison with amplification refractory mutation system (ARMS) in diagnostic samples, and implications for daily routine.Semantic proximity Read ↗

Laboratory detection of JAK2V617F in human myeloproliferative neoplasms.Semantic proximity Read ↗

Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform.Semantic proximity Read ↗

A novel, highly sensitive and rapid allele-specific loop-mediated amplification assay for the detection of the JAK2V617F mutation in chronic myeloproliferative neoplasms.Semantic proximity Read ↗

Detection of the JAK2V617F mutation by asymmetric PCR and melt curve analysis.Semantic proximity Read ↗

Detection of acquired Janus kinase 2 V617F mutation in myeloproliferative disorders by fluorescence melting curve analysis.Semantic proximity Read ↗

Comparative study of different methodologies to detect the JAK2 V617F mutation in chronic BCR-ABL1 negative myeloproliferative neoplasmsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.