Article
Laboratory detection of JAK2V617F in human myeloproliferative neoplasms.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Kui Jonathan S, Espinal-Witter Rosanny, Wang Y Lynn
Abstract excerpt
Recently, a point mutation in the JAK2 gene, JAK2 (V617F) , was discovered in several myeloid proliferative neoplasms including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). Demonstration of the mutation and other similar mutations has now become one of the major criteria in the diagnosis of these neoplasms in the revised World Health Organization Classification of...
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