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Article

Detection of acquired Janus kinase 2 V617F mutation in myeloproliferative disorders by fluorescence melting curve analysis.

Molecular diagnosis & therapy - 1 Jan 2006

Reading N Scott, Lim Megan S, Elenitoba-Johnson Kojo S J

Abstract excerpt

BACKGROUND: The genetic lesion underlying the pathogenesis of chronic myeloproliferative disorders (MPDs) has been identified in the Janus kinase 2 (JAK2) gene. A point mutation in codon 617 causes a valine to phenylalanine substitution (V617F) in the JH2 autoinhibitory region of the protein, res...

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Source

Identifiers

PMID: 17022694
DOI: 10.1007/BF03256206

Genes

JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17022694-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Detection of acquired Janus kinase 2 V617F mutation in myeloproliferative disorders by fluorescence melting curve analysis.PMID 17022694Read ↗

Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis.Semantic proximity Read ↗

Identification of theJAK2V617F Mutation in Chronic Myeloproliferative Disorders Using FRET Probes and Melting Curve AnalysisSemantic proximity Read ↗

Rapid identification of heterozygous or homozygous JAK2(V617F) mutations in myeloproliferative neoplasms using melting curve analysis.Semantic proximity Read ↗

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Detection of the JAK2(V617F) mutation in myeloproliferative disorders by melting curve analysis using the LightCycler system.Semantic proximity Read ↗

Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform.Semantic proximity Read ↗

Optimization of a Low-Cost, Sensitive PNA Clamping PCR Method for JAK2 V617F Variant Detection.Semantic proximity Read ↗

Validating the Sensitivity of High-Resolution Melting Analysis for JAK2 V617F Mutation in the Clinical Setting.Semantic proximity Read ↗

Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis.Semantic proximity Read ↗

Quantitative assay for the detection of the V617F variant in the Janus kinase 2 (JAK2) gene using the Luminex xMAP technology.Semantic proximity Read ↗

Clinical Performance of <i>JAK2</i> V617F Mutation Detection Assays in a Molecular Diagnostics LaboratorySemantic proximity Read ↗

Mutation detection using fluorescent hybridization probes and melting curve analysis.Semantic proximity Read ↗

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