Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis.

American journal of clinical pathology - 1 Apr 2006

Murugesan Gurunathan, Aboudola Samer, Szpurka Hadrian, Verbic Mary Ann, Maciejewski Jaroslaw P, Tubbs Raymond R, Hsi Eric D

Abstract excerpt

We developed and validated a real-time polymerase chain reaction assay using fluorescent hybridization probes and melting curve analysis to identify the JAK2 V617F mutation, which is implicated in a substantial proportion of chronic myeloproliferative disorders (CMPDs). DNA from 161 samples was i...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Fluorescence Resonance Energy Transfer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Formaldehyde

Share to Granulocytes

Share to Janus Kinase 2

Share to Myeloproliferative Disorders

Share to Tissue Fixation

Share to Transition Temperature

Source

Identifiers

PMID: 16627272
DOI: 10.1309/TK0X-L917-XK2V-LRPQ

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16627272-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis.PMID 16627272Read ↗

Identification of theJAK2V617F Mutation in Chronic Myeloproliferative Disorders Using FRET Probes and Melting Curve AnalysisSemantic proximity Read ↗

Rapid identification of heterozygous or homozygous JAK2(V617F) mutations in myeloproliferative neoplasms using melting curve analysis.Semantic proximity Read ↗

Detection of the JAK2(V617F) mutation in myeloproliferative disorders by melting curve analysis using the LightCycler system.Semantic proximity Read ↗

Detection of acquired Janus kinase 2 V617F mutation in myeloproliferative disorders by fluorescence melting curve analysis.Semantic proximity Read ↗

Comparative study of different methodologies to detect the JAK2 V617F mutation in chronic BCR-ABL1 negative myeloproliferative neoplasmsSemantic proximity Read ↗

Clinical Performance of <i>JAK2</i> V617F Mutation Detection Assays in a Molecular Diagnostics LaboratorySemantic proximity Read ↗

Detection of the JAK2V617F mutation by asymmetric PCR and melt curve analysis.Semantic proximity Read ↗

Melting curve analysis after T allele enrichment (MelcaTle) as a highly sensitive and reliable method for detecting the JAK2V617F mutation.Semantic proximity Read ↗

JAK2 V617F in myeloid disorders: molecular diagnostic techniques and their clinical utility: a paper from the 2005 William Beaumont Hospital Symposium on Molecular Pathology.Semantic proximity Read ↗

Mutation detection using fluorescent hybridization probes and melting curve analysis.Semantic proximity Read ↗

Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis.Semantic proximity Read ↗

Validating the Sensitivity of High-Resolution Melting Analysis for JAK2 V617F Mutation in the Clinical Setting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.