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Article

Rapid identification of heterozygous or homozygous JAK2(V617F) mutations in myeloproliferative neoplasms using melting curve analysis.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Jan 2012

Ho Ching-Liang, Wu Yi-Ying, Hung Hsiu-Man, Chang Ping-Ying, Kao Wei-You, Chen Yeu-Chin, Chao Tsu-Yi

Abstract excerpt

BACKGROUND/PURPOSE: The activating JAK2 mutation with a G-C to T-A transversion at codon 617 (JAK2(V617F)) is associated with myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis. Here, we report a technical advance in the diagnosis of JAK2(V617F) in MPNs by melting curve analysis (MCA). METHODS: From January through December 2006, we...

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Source

Identifiers

PMID: 22333011
DOI: 10.1016/j.jfma.2012.01.003

Genes

JAK2
BCR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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