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Article

Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform.

Clinica chimica acta; international journal of clinical chemistry - 14 Dec 2010

Qian Jun, Lin Jiang, Yao Dong-Ming, Chen Qin, Xiao Gao-Fei, Ji Run-Bi, Li Yun, Yang Jing, Qian Zhen

Abstract excerpt

BACKGROUND: Detection of the JAK2 mutation has recently been included under the essential diagnostic criteria for myeloproliferative neoplasm (MPN). High-resolution melt (HRM) curve analysis, a nongel-based, automated system, is introduced as a means of mutation scanning without the requirement of any post-PCR handling. METHODS: We studied the sensitivity and reproducibility of LightScanner™ platform in the...

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Source

Identifiers

PMID: 20728437
DOI: 10.1016/j.cca.2010.08.020

Genes

JAK2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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