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Article

Genomic signatures of positive selection in humans and the limits of outlier approaches.

Genome research - 1 Aug 2006

Kelley Joanna L, Madeoy Jennifer, Calhoun John C, Swanson Willie, Akey Joshua M

Abstract excerpt

Identifying regions of the human genome that have been targets of positive selection will provide important insights into recent human evolutionary history and may facilitate the search for complex disease genes. However, the confounding effects of population demographic history and selection on patterns of genetic variation complicate inferences of selection when a small number of loci are studied. To this end,...

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PMID: 16825663
DOI: 10.1101/gr.5157306
PMCID: PMC1524870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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