Article
Interrogating 11 fast-evolving genes for signatures of recent positive selection in worldwide human populations.
Molecular biology and evolution - 1 Oct 2009
Moreno-Estrada Andrés, Tang Kun, Sikora Martin, Marquès-Bonet Tomàs, Casals Ferran, Navarro Arcadi, Calafell Francesc, Bertranpetit Jaume, Stoneking Mark, Bosch Elena
Abstract excerpt
Different signatures of natural selection persist over varying time scales in our genome, revealing possible episodes of adaptative evolution during human history. Here, we identify genes showing signatures of ancestral positive selection in the human lineage and investigate whether some of those genes have been evolving adaptatively in extant human populations. Specifically, we compared more than 11,000 human...
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