Article
Genomic landscape of positive natural selection in Northern European populations.
European journal of human genetics : EJHG - 1 Apr 2010
Lappalainen Tuuli, Salmela Elina, Andersen Peter M, Dahlman-Wright Karin, Sistonen Pertti, Savontaus Marja-Liisa, Schreiber Stefan, Lahermo Päivi, Kere Juha
Abstract excerpt
Analyzing genetic variation of human populations for detecting loci that have been affected by positive natural selection is important for understanding adaptive history and phenotypic variation in humans. In this study, we analyzed recent positive selection in Northern Europe from genome-wide data sets of 250 000 and 500 000 single-nucleotide polymorphisms (SNPs) in a total of 999 individuals from Great Britain,...
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