Article
Signals of recent positive selection in a worldwide sample of human populations.
Genome research - 1 May 2009
Pickrell Joseph K, Coop Graham, Novembre John, Kudaravalli Sridhar, Li Jun Z, Absher Devin, Srinivasan Balaji S, Barsh Gregory S, Myers Richard M, Feldman Marcus W, Pritchard Jonathan K
Abstract excerpt
Genome-wide scans for recent positive selection in humans have yielded insight into the mechanisms underlying the extensive phenotypic diversity in our species, but have focused on a limited number of populations. Here, we present an analysis of recent selection in a global sample of 53 populations, using genotype data from the Human Genome Diversity-CEPH Panel. We refine the geographic distributions of known...
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