Article
Planar polarity is positively regulated by casein kinase Iepsilon in Drosophila.
Current biology : CB - 11 Jul 2006
Strutt Helen, Price Mary Ann, Strutt David
Abstract excerpt
Members of the casein kinase I (CKI) family have been implicated in regulating canonical Wnt/Wingless (Wg) signaling by phosphorylating multiple pathway components. Overexpression of CKI in vertebrate embryos activates Wg signaling, and one target is thought to be the cytoplasmic effector Dishevelled (Dsh), which is an in vitro target of CKI phosphorylation. Phosphorylation of Dsh by CKI has also been suggested...
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