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Article

Novel regulators of planar cell polarity: a genetic analysis in Drosophila.

Genetics - 1 May 2012

Weber Ursula, Gault William J, Olguin Patricio, Serysheva Ekaterina, Mlodzik Marek

Abstract excerpt

Planar cell polarity (PCP) is a common feature of many epithelia and epithelial organs. Although progress has been made in the dissection of molecular mechanisms regulating PCP, many questions remain. Here we describe a screen to identify novel PCP regulators in Drosophila. We employed mild gain-of-function (GOF) phenotypes of two cytoplasmic Frizzled (Fz)/PCP core components, Diego (Dgo) and Prickle (Pk), and...

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Identifiers

PMID: 22391484
DOI: 10.1534/genetics.111.137190
PMCID: PMC3338256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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