Article
The casein kinase I family in Wnt signaling.
Developmental biology - 15 Jul 2001
McKay R M, Peters J M, Graff J M
Abstract excerpt
The canonical Wnt-signaling pathway is critical for many aspects of development, and mutations in components of the Wnt pathway are carcinogenic. Recently, sufficiency tests identified casein kinase Iepsilon (CKIepsilon) as a positive component of the canonical Wnt/beta-catenin pathway, and necessity tests showed that CKIepsilon is required in vertebrates to transduce Wnt signals. In addition to CKIepsilon, the...
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