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Article

Casein kinase I transduces Wnt signals.

Nature - 23 Sept 1999

Peters J M, McKay R M, McKay J P, Graff J M

Abstract excerpt

The Wnt signalling cascade is essential for the development of both invertebrates and vertebrates, and is altered during tumorigenesis. Although a general framework for Wnt signalling has been elucidated, not all of the components have been identified. Here we describe a serine kinase, casein kinase I (CKI), which was isolated by expression cloning in Xenopus embryos. CKI reproduces several properties of Wnt...

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Identifiers

PMID: 10517632
DOI: 10.1038/43830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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