Article
BMP action in skeletogenesis involves attenuation of retinoid signaling.
The Journal of cell biology - 3 Jul 2006
Hoffman Lisa M, Garcha Kamal, Karamboulas Konstantina, Cowan Matthew F, Drysdale Linsay M, Horton William A, Underhill T Michael
Abstract excerpt
The bone morphogenetic protein (BMP) and growth and differentiation factor (GDF) signaling pathways have well-established and essential roles within the developing skeleton in coordinating the formation of cartilaginous anlagen. However, the identification of bona fide targets that underlie the action of these signaling molecules in chondrogenesis has remained elusive. We have identified the gene for the retinoic...
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