Article
Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways.
The Journal of cell biology - 21 Feb 2000
Weston A D, Rosen V, Chandraratna R A, Underhill T M
Abstract excerpt
The generation of the paraxial skeleton requires that commitment and differentiation of skeletal progenitors is precisely coordinated during limb outgrowth. Several signaling molecules have been identified that are important in specifying the pattern of these skeletal primordia. Very little is known, however, about the mechanisms regulating the differentiation of limb mesenchyme into chondrocytes. Overexpression...
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