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Article

BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways.

Development (Cambridge, England) - 1 Dec 2006

Yoon Byeong S, Pogue Robert, Ovchinnikov Dmitri A, Yoshii Isaac, Mishina Yuji, Behringer Richard R, Lyons Karen M

Abstract excerpt

Bone morphogenetic protein (BMP) signaling pathways are essential regulators of chondrogenesis. However, the roles of these pathways in vivo are not well understood. Limb-culture studies have provided a number of essential insights, including the demonstration that BMP pathways are required for chondrocyte proliferation and differentiation. However, limb-culture studies have yielded contradictory results; some...

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Source

Identifiers

PMID: 17065231
DOI: 10.1242/dev.02680

Genes

FGFR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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