Article

Retinoic acid signaling suppresses chondrocyte identity during cartilage development and regeneration

2024-05-11

Abstract excerpt

Cartilage is a dynamic tissue during development, repair, and disease. Within developing endochondral bones, chondrocytes at growth plate edges transition to osteoblasts, adipocytes, and other connective tissue in the marrow cavity, and in diseases such as Multiple Osteochondromas (MO) chondrocytes form abnormally around growth plates and contribute to ectopic bone. On the other hand, the inability to form new cho...

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Literature Corpus work: 59c2425d-1302-595b-bc28-c8ee1e6a01e4
DOI: 10.1101/2024.05.10.593640

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