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Bone Morphogenetic Protein (BMP) signaling in development and human diseases

27 Jul 2014

Abstract excerpt

Bone Morphogenetic Proteins (BMPs) are a group of signaling molecules that belongs to the Transforming Growth Factor-β (TGF-β) superfamily of proteins. Initially discovered for their ability to induce bone formation, BMPs are now known to play crucial roles in all organ systems. BMPs are important in embryogenesis and development, and also in maintenance of adult tissue homeostasis. Mouse knockout models of...

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PMID: 25401122
DOI: 10.1016/j.gendis.2014.07.005

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