Article
Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld.
The Journal of biological chemistry - 1 Sept 2006
Jones Lindsay L, Brophy Susan E, Bankovich Alexander J, Colf Leremy A, Hanick Nicole A, Garcia K Christopher, Kranz David M
Abstract excerpt
The major histocompatibility complex (MHC) is the most polymorphic locus known, with thousands of allelic variants. There is considerable interest in understanding the diversity of structures and peptide-binding features represented by this class of proteins. Although many MHC proteins have been crystallized, others have not been amenable to structural or biochemical studies due to problems with expression or...
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