Article
Recognition of shared melanoma antigens in association with major HLA-A alleles by tumor infiltrating T lymphocytes from 123 patients with melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jan 2000
Kawakami Y, Dang N, Wang X, Tupesis J, Robbins P F, Wang R F, Wunderlich J R, Yannelli J R, Rosenberg S A
Abstract excerpt
A total of 123 tumor-infiltrating T lymphocyte (TIL) cultures established from patients with HLA-A1, -A2, -A3, -A24, or -A31 metastatic melanoma in the Surgery Branch, National Cancer Institute, were screened for recognition of shared melanoma antigens including five melanosomal proteins (tyrosinase, MART-1/melan-A, gp100, TRP1, TRP2) as well as peptides derived from MAGE-1 and MAGE-3. Examination of the...
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