Article
Multiple HLA class II-restricted melanocyte differentiation antigens are recognized by tumor-infiltrating lymphocytes from a patient with melanoma.
Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2002
Robbins Paul F, El-Gamil Mona, Li Yong F, Zeng Gang, Dudley Mark, Rosenberg Steven A
Abstract excerpt
Dramatic clinical responses were observed in patient 888 following the adoptive transfer of autologous tumor-infiltrating lymphocytes (TIL). Previously, extensive analysis of the specificity of class I-restricted T cells from patient 888 TIL has revealed that these T cells recognize a mutated, as well as several nonmutated tumor Ags. Additional studies that were conducted on TIL from patient 888 indicated that...
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